Paralysis Research Today is a free monthly online journal that collates and summarizes the latest research about Paralysis, including details on treatment, diagnosis, facial paralysis, sleep paralysis.

Superior mediastinal syndrome with Rowland-Payne syndrome: an unusual presentation of cervico-mediastinal neuroblastoma.

Kapoor V, Lodha R, Agarwala S

Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India.

A 5-month-old boy presented with superior mediastinal syndrome due to a large, unresectable cervico-mediastinal neuroblastoma. He had an unusual constellation of findings not previously reported in neuroblastoma: Horner syndrome, phrenic nerve palsy, and palsy of the ipsilateral recurrent laryngeal nerve. This constellation of findings in adult malignancies is termed the Rowland-Payne syndrome. The child required prolonged mechanical ventilation but responded to chemotherapy and is now free of tumor and completely recovered.

Published 4 February 2005 in Pediatr Blood Cancer, 44(3): 280-2.
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