Paralysis Research Today is a free monthly online journal that collates and summarizes the latest research about Paralysis, including details on treatment, diagnosis, facial paralysis, sleep paralysis.

Progressive supranuclear palsy-like phenotype associated with bilateral hypoxic-ischemic striopallidal lesions.

Kim HT, Shields S, Bhatia KP, Quinn N

National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom.

A progressive supranuclear palsy (PSP)-like syndrome due to vascular or anoxic brain insult is rare. We describe a 65-year-old man with a progressive PSP-like phenotype associated with hypoxic-ischemic bilateral striopallidal lesions, secondary to rupture of and subsequent surgery for a thoracic aortic aneurysm. After early extrapyramidal features, 10 months later he started to fall, and developed levator inhibition. A supranuclear gaze palsy for downgaze was documented 5.5 years after the insult.

Published 6 June 2005 in Mov Disord, 20(6): 755-7.
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